Content: The theoretical part covers the following aspects: Legal foundations: ApBetrO, PIC-Guide, TRGS 525, GMP guidelines, ADKA guideline, BAK guideline GMP-compliant pharmaceutical production: A practical report Entry procedures: materials, personnel, sluice concepts Microbiological validation: validation procedures, nutrient medium filling, sterility testing, environmental monitoring, documentation Microbiological monitoring: particle and airborne microbial measurements, contact plate sampling, sample evaluation: requirements such as incubation time, various nutrient media, documentation of results: handling deviations, setting warning and action limits) + documentation of the results Safety cabinets: function, differences, classification, filters, filter changes, recirculation and exhaust air procedures, etc. Demo: visualization using smoke tests in a safety cabinet: product protection, contamination prevention Working methods for isolators vs. safety cabinets Pharmaceutical aspects: drug effects, aseptic preparation of parenterals, etc. During the internship, the following topics are covered in groups at various workstations: Aseptic preparation: practical work according to GMP guidelines - how does it work? Including behavior in cleanrooms and at safety cabinets, influence of rapid movements, ... Microbiological monitoring: contact plate sampling, active air microbial collection, critical points, correct procedures, etc. Cleaning and disinfection: VAH list, hygiene plan, documentation, differences in the mode of action and application of disinfectants: bactericidal/sporicidal agents, spray vs. wipe disinfection, practical tips Practice clothing concepts, sterile dressing procedures, hand disinfection, proper behavior in the cleanroom Target group: pharmacists, doctors, pharmacy technicians, medical technical assistants, safety officers, nursing staff, technical personnel, monitoring personnel, laboratory planners, laboratory managers