Premiere for the Noack N 760 blister packaging machine

Blistermaschine N 760 von Romaco Noack / N 760 blister packaging machine by Romaco Noack

Wirbelschichtprozessor VENTILUS® Pilot von Romaco Innojet / VENTILUS® Pilot fluid bed processor by Romaco Innojet

Containment-Tablettenpresse KTP 420X C von Romaco Kilian / KTP 420X C containment tablet press by Romaco Kilian

The N 760 blister packaging machine from Romaco Noack will be making its trade fair debut at this year’s PCI Days in Warsaw, Poland. Romaco, the one stop solutions supplier, will also be presenting innovative processing technologies that set new standards when it comes to granulating, drying, coating and tableting oral solid dosage forms.

This is the first time that Romaco will be showing the new Noack N 760 platen sealing blister machine at a trade fair. At the upcoming PCI Days in Warsaw, Poland, this compact standalone machine will manufacture recyclable blister packs from PET mono-material.
Romaco will additionally be presenting more key technologies along the pharmaceutical process chain, such as the VENTILUS® Pilot fluid bed processor from Romaco Innojet and the KTP 420X C containment tablet press from Romaco Kilian. The one stop supplier’s solutions for manufacturing and packaging oral solid dosage forms are offered as standalone machines or as fully integrated pharmaceutical lines. They ship in a variety of configurations and performance classes from laboratory-scale models to high-volume production equipment and high-speed packaging lines.

All Romaco technologies share the same focus on sustainable system design and are therefore ideal for energy-efficient production processes that make sparing use of resources, hence reducing the carbon footprint of the end products. In 2024, Romaco was awarded its first-ever gold medal in the EcoVadis sustainability ratings for its commitment to climate protection.

N 760 blister packaging machine by Romaco Noack

The N 760 from Romaco Noack is an intermittent motion blister packaging machine in balcony design for universal use. It is perfect for packaging a very broad range of products from solid dosage forms, ampoules and medical devices to semi-solids. Blisters with a maximum forming area of 155 x 138 mm and a maximum forming depth of 25 mm can be produced in this way. Product changes can be carried out quickly and easily, because only a very few compact and lightweight format parts need to be replaced and all parameters are electronically stored. The N 760 has an exceptionally space-saving layout and is easy to operate, fulfilling all of the requirements of the contract packaging sector, which needs to respond quickly and flexibly at any time to dynamic market situations. With a maximum output of up to 200 blisters per minute, the technology is mainly deployed to produce smaller batch sizes in the low to medium speed segment. The product feeding unit is available in different configurations and is either manual or fully automatic, for example when used with high-tech systems for demanding products or multi-dose blisters. The electrical cabinet can be swung out, meaning the N 760 is readily accessible for maintenance work. Furthermore, the extremely short foil web from the forming station to the die-cutter restricts the amount of waste while running in and retooling the machine to a minimum. Last but not least, the Romaco Noack N 760 blister packaging machine can be optionally connected to a cartoner and a case packer.

Romaco will be taking advantage of PCI Days to demonstrate how the Noack N 760 blister packaging machine manufactures blister packs from recyclable mono-material supplied by Liveo Research. The forming and lidding foils for these blisters are both made of PET (polyethylene terephthalate), which is a sustainable choice for the primary packaging of pharmaceuticals and nutraceuticals. Where products are currently packaged in PVC/aluminum blisters, the PET/PET blisters provide equivalent barrier properties to their PVC/aluminum counterparts.

Kilian KTP 420X C containment press

The containment version of Romaco Kilian’s KTP 420X C rotary tablet press fulfills all requirements for processing active pharmaceutical ingredients up to OEB Level 3 with medium toxicological potency. This includes numerous medications, for example for treating hypertension, ventricular ulcers or bronchial asthma. The containment tablet press is configured with a Restricted Access Barrier System (RABS) featuring glove ports to protect the operator as well as a Rapid Transfer Port (RTP) for contamination-free material transfer. Negative pressure in the compaction area and electric door locks as well as dust-tight docking systems and a dust-tight tablet chute moreover ensure GMP compliance. The efficient implementation of high-quality containment processes is additionally supported by the proven hygienic design of the KTP 420X C. The hermetical separation between the compaction and technical areas prevents tablet dust from entering the mechanical compartment. The compaction area itself is designed as a deep-drawn, single-piece run-off containment with polished surfaces and large radii, so that far less effort is necessary for cleaning. Protective clothing is only required for cleaning the press and is not essential during production. The very good OEE (overall equipment effectiveness) and extremely low TCO (total cost of ownership) are key characteristics of the Romaco Kilian KTP 420X C. With a maximum output of 475,200 tablets per hour, the technology is classed as a high-speed press for containment applications.

VENTILUS® Pilot fluid bed processor from Romaco Innojet

The VENTILUS® Pilot fluid bed processor from Romaco Innojet is a mobile allrounder for pilot scale applications or small batches. The technology impresses with excellent results in terms of flow properties as well as powder and granulate compressibility. Mounted on four wheels, this compact machine fits through any standard door frame and is designed for plug and play installation. An all-in-one solution intended for batch sizes from 4 to 25 liters, it granulates, dries or coats particles of any size from 10 μm to 2 mm. The technology meets all the requirements for laboratory use as well as for GMP-compliant production of clinical samples. The spray liquid is applied optionally according to the conventional top spray method or using a bottom spray system with a central nozzle – either the ROTOJET® or the new FLEXIJET®. The latter was specifically developed for granulation processes and is not only very easy to handle, but also quick to clean. The cylindrical container featuring the ORBITER® booster permits controlled, gentle batch intermixing. The homogeneous flow conditions improve product quality and reduce the spray liquid consumption while simplifying scale-ups. In addition, the VENTILUS® Pilot is suited for hot melt coating processes, which merely requires connection of the patented Innojet IHD hot melt system. The processing time is consequently up to 85 percent shorter and the processor’s carbon footprint is significantly lower.