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All publications on the branch Pharmaceutical industry / biotechnology

In order for vaccines to be produced reliably and in sufficient quantities, depending on the production method, the appropriate technical equipment, such as hygienic and high-precision pumps, is required. (Source: Gerd Altmann, pixabay) To avoid mixing errors, the pumps were designed in the triplex variant, i.e., with three pump heads per pump and motor. This meant that a pulsation damper was not necessary. (Source: LEWA GmbH) The project team consisting of Mr. Dastig, Mr. Sommer, Mr. Marinoff, Ms. Yermolina, Mr. Topousidis, and Mr. Graze (from left to right). (Source: LEWA GmbH) The project team consisting of Ms. Yermolina, Mr. Dastig, Mr. Sommer, Mr. Marinoff, Mr. Topousidis, and Mr. Graze (clockwise). (Source: LEWA GmbH)
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  • Corona

Vaccine production in Europe - Multi-head system and low shearing effect ensure gentle dosing process

Constant conveying without pulsation: German pump expert supplies high-precision diaphragm pumps for vaccine production in the shortest time possible

Since the start of the COVID-19 pandemic, numerous countries around the world have been working hard to develop new vaccines against the virus. A U.S. pharmaceutical company based in Italy will also be involved in the mass production of the vaccine and is preparing for it. There must be no dosing er…
Granules are the basis of numerous products in the pharmaceutical and food sectors; they are subject to the strictest quality requirements. (Source: Mizianitka / Pixabay.com) Based on numerous test series and optimizations in measurement technology, a market-ready roll press for dry granulation with integrated diagnostic tool has been developed. (Source: Alexanderwerk GmbH) Roller press WP120 with installed inline particle probe IPP 75-S. (Source: Alexanderwerk GmbH) So that no manual sampling and offline analysis are necessary for quality assurance, but all measurements and analyses can already be performed inline and in real time, the inline particle probe is equipped with a newly developed process interface for representative measurement. (Source: Parsum GmbH) The machine control (here shown as a screen plot) displays the temporal course of various exemplary values such as the set pressing force in red, the resulting X10 of the particle size distribution in green, and the resulting virtual sieve fraction 0-125 μm in blue. A clear change in the ratio between the granulate and fine fraction is evident, which can be depicted with a slight time delay of approximately 60 seconds. (Source: Alexanderwerk GmbH)
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  • Systems

Inline measurement technology in the pharmaceutical, chemical and food industries - Plant manufacturer and measurement technology specialist develop PAT solutions for continuous manufacturing in R&D collaboration

Quality assurance without loss of time: roller press with PAT interface monitors particle size of continuously produced granules in real time

Until now, the quality of many end and intermediate products in the chemical, pharmaceutical and food industries has been determined by time-consuming laboratory analyses. As a result, product quality is only assessed retrospectively. This causes large time delays in the release of produced batches…
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